ENROLL IN THE EPILEPSY RESEARCH STUDY
About the Study
If you, or a loved one, are suffering from epilepsy, there is hope. Medical and non-profit organizations are working tirelessly to find treatments and a cure. Part of the process of discovering effective treatments for epilepsy are clinical trials. These research studies and clinical trials are separated into phases, and are offered to patients with epilepsy after pre-clinical trials and early phase studies are completed.
An epilepsy clinical trial offers patients the opportunity to receive care from some of the nation’s leading neurologists, and includes treatment and continued monitoring at no cost to the patient, with expenses for time and travel potentially reimbursed as well.
The Neurological Research Center at the Fort Wayne Neurological Center is currently enrolling for a clinical study to assess the effectiveness of a new treatment option for patients with epilepsy.
If you are currently suffering from epilepsy, please review the following qualifications and submit a form below to find out if you qualify for this study. To learn more about participating in a study at the neurological research center read our patient FAQ page or contact us with additional questions.
You may qualify for the Epilepsy study if you must meet the following criteria.
Age: 18 years and older
Gender: Male or Female
- Diagnosis of focal epilepsy according to the 1989 International League Against Epilepsy (ILAE) criteria at least 3 years before study entry.
- Subject has failed to achieve seizure control with greater than or equal to 4 tolerated and appropriately chosen prior antiepileptic drugs (AED), including past and ongoing treatment, that were individually optimized for adequate dose and duration. Prior discontinued AED treatment would need to be assessed by the Investigator considering the patient medical records and patient and/or caregiver interview.
- Average of greater than or equal to 4 spontaneous and observable focal seizures (type IA1 (focal aware), IB (focal impaired awareness), IC (focal to bilateral tonic-clonic)) per month.
- Current treatment with an individually optimized and stable dose of at least 1 and up to 3 antiepileptic drugs (AEDs) for the 8 weeks prior to the Screening Visit.
If some of the following apply, you MAY NOT qualify for this study.
- Subject has a history of or signs of generalized or combined generalized and focal epilepsy.
- Cluster seizures which are uncountable in the previous 8 weeks before study entry and during 4 weeks prospective baseline.
- Current treatment with carbamazepine, phenytoin, primidone, phenobarbital.
- Current treatment/ use of (non-AED) prescription, nonprescription, dietary (eg, grapefruit or passion fruit), or herbal products that are potent inducers or inhibitors of the CYP3A4 or 2C19 pathway for 2 weeks prior to the Baseline Visit.
- Subjects taking sensitive substrates of CYP2C19 for 2 weeks prior to the Baseline Visit.
- Subject has been taking vigabatrin less than 2 years at study entry.
- Subject has been taking felbamate for less than 12 months.
- Subject taking retigabine for less than 4 years.
- Subject has a current medical condition that occurred within the last 12 months which, in the opinion of the investigator, could compromise his/her safety or ability to participate in this study.
See if you qualify for this study
Resources for Epilepsy Patients
We know that an epilepsy diagnosis is a challenging prospect to face. We’re here to help. We want to provide you with every available resource to equip and help you on your health journey. We’ve created a list of organizations that are actively working to find answers, provide information, discover new treatments, and who are relentlessly advocating on your behalf.
The Epilepsy Foundation’s ultimate goal is to see a world free of epilepsy. They do this through raising awareness, addressing the challenges people with epilepsy face, and driving research to accelerate therapies into the hands of people who need them.
Visit Website: https://www.epilepsy.com
The CDC has created a resource for people who have been diagnosed with Epilepsy. It includes facts and statistics, publications on epilepsy, and information for parents and caregivers, professionals, and schools to help raise awareness and training for how to help best.
Visit Website: https://www.cdc.gov/epilepsy/index.html
Seizure Link has created a device that alerts individuals and caregivers to when a seizure is about to happen. It comfortably fits on your arm and alerts caregivers on their mobile devices. Their goal is to help reduce stress and anxiety that comes from the unpredictable nature of seizures.
Visit Website: https://seizurelink.com
The ILAE is to promote research, education, and training about epilepsy for the purpose of improving services and care for patients and families. Their national chapter in the United States is the American Epilepsy Society – https://www.aesnet.org. They offer comprehensive access to the latest research, clinical resources, and education.
Visit Website: https://www.ilae.org/about-ilae